PhD candidate MRI-guided radiotherapy

UMC Utrecht

UMC Utrecht

Regio Utrecht
Vaste aanstelling
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Cancer radiotherapy aims to destroy tumours by delivering a high radiation dose. The recent introduction of the hybrid MRI-linear accelerator radiotherapy machine (Elekta Unity) has the potential to transform cancer therapies by enabling online imaging during treatment and thus allowing for better tumour targeting and more sparing of healthy tissue. The University Medical Centre Utrecht has played a key role in the research and development of this 1.5 T MR-linac, which is now used clinically since 2018. We are currently looking for potential candidates with a Natural Science background and a strong programming focus for a PhD position that aims to research and develop novel software components and modular pipelines that will take full advantage of the machine’s hardware capabilities. Starting from the current clinical available workflows during which the treatment is modified once during every fraction to target the daily anatomy of the patient, new treatment pipelines will be developed and introduced to the clinic performing intra-fraction monitoring and adaptation with increasing levels of complexity. An essential part of these pipelines will be a robust and fast treatment software that monitors the anatomical motion of the patient, keeps track of the true delivered dose, and adapts the radiation delivery on the fly accordingly based on these inputs. The online requirements of these applications require fast, optimized and robust code implementations to ensure safe clinical usage. The candidate will explore and develop optimal adaptive workflows on a treatment site-specific basis and should be comfortable with modifying existing as well as implementing new software features for the various components of these workflows. The goal is to show the potential benefits of the newly created workflows and introduce them in clinical practice.


The main research focus of the department is MRI guided Radiotherapy. A hybrid 1.5T MRI radiotherapy system has been invented, developed and clinically implemented in close collaboration with industrial partners Elekta and Philips. The research spans from clinical topics such as quality of life and initiating clinical trials, to computational work on real-time dose optimization and deep learning on adaptive radiotherapy, to hardware development such as new MRI RF coils. This offers a heterogeneous, yet focussed, research environment for new PhD candidates.


We are looking for candidates with a master degree with a natural science background such as a computer scientist, computational physicist or alike.

The maximum salary for this position (100%) is € 3.020,00 gross per month based on full-time employment (work week 36 hours). This job is based on a temporary position for 4 years.

In addition, we offer an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities. The terms of employment are in accordance with the Cao University Medical Centers (UMC).

More information

If you have any questions about this vacancy, please contact Mr.B.W. Raaymakers, Prof.dr., phone number: contactinformatie 6, e-mail adress:

Acquisition based on this jobopening is not appreciated.

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